Effect of gradient of stress intensity factor at a crack tip on fatigue crack growth and correction method for the effect

The stress intensity factor can be applied as an evaluation parameter of crack growth under small-scale yielding conditions.Moreover, the stress intensity factor corrected by the plastic zone correction can potentially be used as an evaluation parameter of crack growth for small-scale yielding criteria or beyond these criteria.In the previous study

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Targeting autophagy can synergize the efficacy of immune checkpoint inhibitors against therapeutic resistance: New promising strategy to reinvigorate cancer therapy

Immune checkpoints are a set of inhibitory and stimulatory molecules/mechanisms that affect the activity of immune cells to maintain the existing balance between pro- and anti-inflammatory signaling pathways and avoid the progression of autoimmune disorders.Tumor cells can employ these checkpoints to evade immune system.The discovery and developmen

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Retropharyngeal carotid artery stenosis; potential for minimizing operative complications utilizing transcarotid artery stent revascularization

Retropharyngeal carotid artery occlusive disease presents a formidable challenge for surgeons due to its anatomic location and increased potential for complications.Conventional treatments, including open read more revascularization and transfemoral stenting, often face limitations.Transcarotid artery revascularization (TCAR) has offered a promisin

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